PREHEAT oven to 450°F. Line a baking sheet with aluminum foil and spray with nonstick cooking spray. In a medium mixing bowl, combine Brussels sprouts, ghee, balsamic vinegar, black pepper and half of sea salt. Toss to coat. Pour brussels sprouts onion baking sheet and bake for 10 minutes.
IN a small bowl, combine smoked paprika, onion powder, garlic powder, oregano and remaining sea salt. Stir to combine. Pat any excess moisture from salmon using a paper towel. Sprinkle seasoning over both sides of salmon and use hands to gently rub into salmon.
REMOVE brussels sprouts from oven and make a space for the salmon. Place pan back into oven for 15 minutes.